Vorm Ziekte Thema Locatie

ERS 2016: WNT-4 regulates pro-inflammatory responses driven by epithelial- mesenchymal cross-talk (PA5067)

  • Spanjer, A
  • Dept. of Molecular Pharmacology and Groningen Research Institute for Asthma and COPD (GRIAC) - University of Groningen
  • 14 november 2016
  • (
  • afgerond project

Epithelial-fibroblast communication is an important aspect in the pathophysiology of chronic obstructive pulmonary disease (COPD). COPD is an obstructive lung disease, that is characterized by chronic inflammation, emphysema, mucus hypersecretion, fibrosis and remodeling in the small airways and lung tissue [1]. During the European Respiratory Society (ERS) annual conference 2016, Professor And...

Keyword: ERS 2016 COPD WNT-4 emphysema

Effects of the Novel Pharmacological Compaou nd Sul-121 on LPS-Induced Airway Neutrophilia

  • Han B.
  • Rijks Universiteit Groningen
  • 22 augustus 2016
  • afgerond project

Keyword: ATS 2016 COPD Oxidative stress

Astma: update in epidemiologie, behandeling en exacerbaties

  • Engelkes, M.
  • Erasmus Universiteit Rotterdam
  • 8 juli 2016

Er is behoefte aan up-to-date gegevens over astma uit de dagelijkse klinische praktijk. Marjolein Engelkes onderzocht de epidemiologie, behandeling en exacerbaties bij astmapatiënten.

Keyword: Astma epidemiologie exacerbaties kinderen therapietrouw inhalatiemedicatie sterfte.

Transforming growth factor beta affects miRNA expression in control and COPD fibroblasts

  • Ong, Jennie
  • Universitair Medisch Centrum Groningen/Rijksuniversiteit Groningen
  • 20 juni 2016
  • (
  • afgerond project

Chronic obstructive pulmonary disease (COPD) is characterized by aberrant lung tissue repair and remodeling with high levels of transforming growth factor beta (TGF-β) (1). Lung fibroblasts, activated by TGF-β, play a key role in this process (2). The TGF-β pathway is a main factor in extracellular matrix (ECM) production. An important aspect is that TGF-β can influence the ...

Keyword: COPD primary lung fibroblasts TGF-β miRNA tissue repair

Pharmacological inhibition of β-catenin/CBP interaction

  • Koopmans, T. PhD
  • Rijks Universiteit Groningen
  • 17 november 2015
  • afgerond project

Pharmacological inhibition of β-catenin/CBP interaction with the small molecule ICG-001 inhibits proliferation and extracellular matrix production in airway smooth muscle.

Keyword: Asthma β-catenin airway smooth muscle ATS 2015

Critical, environmental & genetic predictors of peak expiratory flow

  • Loohuis, A.M.M. Msc.
  • Rijks Universiteit Groningen
  • 12 november 2015
  • afgerond project

Clinical, environmental and genetic predictors of peak expiratory flow variability in asthma patients.

Keyword: astma piekstroomvariabiliteit

The anti-inflammatory and bronchodilating properties of the novel pharmacological compound Sul-121

  • Han, Bing
  • Rijksuniversiteit Groningen
  • 24 september 2015
  • afgerond project

The American Thoracic Society (ATS) is a nonprofit organization focused on improving care for pulmonary diseases,critical illnesses and sleep-related breathing disorders. The celebration of the llOth anniversary of the founding of the Society culminated at ATS 2015 with a series of special lectures that will feature the major scientific and clinical breakthroughs in our fields. Below are the re...

Keyword: ATS 2015 Cigarete smoke COPD Sul-121

Developmental and pathologic roles of Follistatin-like 1 in the lung

  • Tania, N.P.
  • University of Groningen , Department of Molecular Pharmacology
  • 23 september 2015
  • (
  • afgerond project

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that is characterized by airway remodeling, persistent inflammation, and emphysema (1). Patients with COPD suffer from airflow obstruction that is not fully reversible. Extracellular matrix remodeling of the airways and lung tissue is a hallmark of morphological changes in patients with COPD. Excessive production of the ...

Keyword: COPD follistatin like-1 (Fstl1)

Phenotyping of wheezing in preschool children

  • Kant, Kim van der PhD
  • University Maastricht
  • 2 februari 2015
  • afgerond project

The European Respiratory Society (ERS) conference took place from 6 to 10 September 2014 in Munich. The ERS conference is the largest conference on respiratory health and disease worldwide. By attending the ERS conference I was able to present the results of the studies that I conducted during two fellowships: at Imperial College (London, UK)1 and at the Oslo University Hospital (Oslo, Norway)....

Keyword: Asthma preschool children Phenotyping

Does smoking reduction counselling promote abstinence in COPD patients not ready to quit?

  • Hagens, P.
  • Universiteit Twente
  • 2 februari 2015
  • (
  • afgerond project

15th SRNT-Europe Annual Meeting The 15th Annual Meeting of the Society for Research on Nicotine and Tobacco (SRNT) Europe was held from the 18th to the 20th of September 2014 in Santiago de Compostela, Spain. In line with my personal interests and current research project (effects of smoking reduction on cessation in patients with COPD), I will discuss some important topics presented at this...

Keyword: COPD 15th SRNT RTQ

Gratis nieuwsbrief

Blijf op de hoogte van het laatste nieuws over subsidies, zorg en onderzoek naar astma, COPD en andere longziekten.