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Cardiovascular and metabolic risk in patients with COPD and the effect of exercise training

  • Beijers R.J.H.C.G.
  • NUTRIM School of Nutrition and Translation Research in Metabolism Maastricht University Department of Respiratory Medicine
  • 3 januari 2017
  • 7.2.16.125CO (3.4.12.023)
  • afgerond project

Chronic obstructive pulmonary disease (COPD) patients are not only characterized with irreversible airflow limitation but also by extrapulmonary manifestations such as cardiovascular disease and skeletal muscle wasting. Two major phenotypic characteristics for the higher cardiovascular and reduced metabolic health in COPD are abdominal obesity and low muscle mass (1). It is unknown if exercise ...

Keyword: COPD Cardiometabolic risk

ERS 2016: WNT-4 regulates pro-inflammatory responses driven by epithelial- mesenchymal cross-talk (PA5067)

  • Spanjer, A
  • Dept. of Molecular Pharmacology and Groningen Research Institute for Asthma and COPD (GRIAC) - University of Groningen
  • 14 november 2016
  • 7.1.16.141CO (3.2.10.042)
  • afgerond project

Epithelial-fibroblast communication is an important aspect in the pathophysiology of chronic obstructive pulmonary disease (COPD). COPD is an obstructive lung disease, that is characterized by chronic inflammation, emphysema, mucus hypersecretion, fibrosis and remodeling in the small airways and lung tissue [1]. During the European Respiratory Society (ERS) annual conference 2016, Professor And...

Keyword: ERS 2016 COPD WNT-4 emphysema

26th ERS international congress 2016, London

  • Ceelen, J.J.M.
  • NUTRIM School of Nutrition and Translation Research in Metabolism Maastricht University Department: Respiratory medicine
  • 14 november 2016
  • 7.1.16.138CO (3.2.11.036)
  • afgerond project

The goal of the ERS congress is to promote new scientific knowledge and put a spotlight on respiratory research by presenting cutting-edge research alongside informative educational sessions. Oral and poster presentation highlights concerning COPD comorbidities and phenotyping as well as new insights in predicting exacerbations are described below.

Keyword: COPD Penotyping Emphysema

Follistatin-like 1 is crucial for normal postnatal development of the pulmonary vasculature

  • Tania, Navessa P. MSc
  • Department of Molecular Pharmacology University of Groningen
  • 23 augustus 2016
  • 7.1.16.099CO (3.2.12.083)
  • afgerond project

Keyword: COPD comorbidity Follistatin-like 1 pulmonary vasculature

Monitoring Local Pulmonary cAMP Levels

  • Zuo, H.
  • Rijks Universiteit Groningen
  • 23 augustus 2016
  • 7.1.16.104CO
  • afgerond project

American Thoracic Society Report 2016

Keyword: ATS 2016 COPD Cyclic AMP

Immunomodulatory effects of vitamin D

  • Rafiq, Rachida
  • VU University Medical Center, Department of Internal Medicine and Endocrinology
  • 23 augustus 2016
  • 7.2.16.123CO (5.1.13.033)
  • afgerond project

The European Congress on Endocrinology is an annual congress in which the latest developments in basic, translational and clinical research in endocrinology is presented and discussed. During this congress I had the opportunity to present the preliminary results of our pilot trial on the effects of vitamin D supplementation in patients with COPD, and discuss the design of our ongoing trial. Sev...

Keyword: COPD vitamin D T-cells immune system

Effects of the Novel Pharmacological Compaou nd Sul-121 on LPS-Induced Airway Neutrophilia

  • Han B.
  • Rijks Universiteit Groningen
  • 22 augustus 2016
  • 7.1.16.105CO
  • afgerond project

Keyword: ATS 2016 COPD Oxidative stress

Assessment of COPD prevalence

  • Borlée, Floor
  • Universiteit Utrecht IRAS
  • 22 augustus 2016
  • 7.1.16.110CO (3.2.11.022)
  • afgerond project

The American Thoracic Society (ATS), founded in 1905, tries to improve global health by advancing research, patient care, and public health in pulmonary disease, critical illness, and sleep disorders. The ATS organizes yearly an international conference which provides an ideal opportunity for clinicians and researchers to come together to discuss the latest advances in treatment and care. Each ...

Keyword: COPD prevalence ATS 2016 population-based study post-bronchodilator (BD) spirometry

Transforming growth factor beta affects miRNA expression in control and COPD fibroblasts

  • Ong, Jennie
  • Universitair Medisch Centrum Groningen/Rijksuniversiteit Groningen
  • 20 juni 2016
  • 7.1.16.122CO (3.4.12.044)
  • afgerond project

Chronic obstructive pulmonary disease (COPD) is characterized by aberrant lung tissue repair and remodeling with high levels of transforming growth factor beta (TGF-β) (1). Lung fibroblasts, activated by TGF-β, play a key role in this process (2). The TGF-β pathway is a main factor in extracellular matrix (ECM) production. An important aspect is that TGF-β can influence the ...

Keyword: COPD primary lung fibroblasts TGF-β miRNA tissue repair

Ex vivo elastase treatment disrupts Parenchymal Structure

  • Dijk, v. Eline
  • Rijks Universiteit Groningen
  • 7 juni 2016
  • 7.1.16.106CO
  • afgerond project

Ex vivo elastase treatment disrupts Parenchymal Structure and Enhances Airway Narrowing In Precision Cut Lung Slices.  

Keyword: COPD Ex Vivo

Gratis nieuwsbrief

Blijf op de hoogte van het laatste nieuws over subsidies, zorg en onderzoek naar astma, COPD en andere longziekten.